Research · Precedent

How other innovation
districts were built

Twelve districts that were built, the patterns they share, the partners behind each of them, and how the buildings and the money came together.

Research notes · Salem, Oregon · September 2026 · Hero image is a Now City concept render, not one of the districts below
Case Studies

Coalitions that built districts

These places began the same way the district begins: a champion convened partners, a neutral entity was formed, an anchor and a public tool arrived together, and a community was kept close. Their industries range from semiconductors to biotech to clean energy. What the district borrows is the method, the way a coalition turns one building into a district. The closest match to West Salem is the first one.

Closest to us · St. Louis, USA

Cortex Innovation Community

Five anchor institutions, Washington University, BJC HealthCare, Saint Louis University, the University of Missouri-St. Louis, and the Missouri Botanical Garden, came together in 2002 after a university chancellor visited Kendall Square and brought his peers along to see it. They pooled roughly $29 million, formed a single nonprofit master developer, and paired it with Missouri's redevelopment and tax-increment financing powers to transform a brownfield into a district. The lesson for Salem is direct: a handful of anchors, modest pooled equity, one neutral nonprofit, and a public financing tool are enough to begin.

Visit Cortex ↗
406
companies on campus
5,400
people employed
$1.33B
invested in the district
$163.8M
public tax revenue, 2014 to 2025
Cortex 2025 Impact Report

From around the world

All eight international cases, with the lesson from each
Brainport Eindhoven at dusk
Eindhoven, Netherlands

Brainport

A mayor, a university president, and a chamber-of-commerce president convened a standing partnership and held it in the Brainport Foundation. The region became home to ASML, one of the world's most valuable technology companies.

Lesson: form the coalition before the real estate.
~5,000 tech companies · ~73,000 tech jobs · ~40% of all Dutch R&D
Visit ↗
Stockholm, Sweden

Kista · Electrum Foundation

The City of Stockholm and Ericsson created a neutral foundation in 1985; its first act was a single shared building that put KTH university labs next to companies under one roof.

Lesson: a neutral foundation plus one shared building puts people in the same room.
Sweden's largest ICT cluster · founded 1985 · KTH + Ericsson
Visit ↗
Leuven, Belgium

imec · KU Leuven

In 1984 the Flemish government funded a neutral research institute spun out of KU Leuven. Because no single company owns it, the world's rival chipmakers all fund it and use it.

Lesson: a shared, neutral facility does what no one company will.
World-leading chip R&D · founded 1984 · funds rival chipmakers
Visit ↗
Medellín, Colombia

Ruta N

The city and its publicly owned utility created an innovation corporation funded by utility dividends, and seated citizens as a full partner. The district became central to the city's wider transformation.

Lesson: a local revenue engine and a seated community make a district an equity project.
210 companies from 30 countries · 2,800+ innovation jobs
Visit ↗
Adlershof Science City, Berlin
Berlin, Germany

Adlershof Science City

The State of Berlin relocated Humboldt University's science faculties physically onto the site, then grew a science city of around 1,000 companies and 16 research institutes around them.

Lesson: real faculty, labs, and students on site turn a project into a science city.
~1,000 companies · 16 research institutes · ~16,000 employees
Visit ↗
Poblenou, the 22@Barcelona district
Barcelona, Spain

22@Barcelona

The city rezoned 200 hectares of old industrial Poblenou for knowledge work and recycled the value uplift into public infrastructure, drawing three universities and 1,400-plus firms.

Lesson: zoning can be a financing tool, and the community belongs in the plan from day one.
200 hectares · 1,400+ firms · ~90,000 jobs
Visit ↗
Cambridge, UK

Cambridge Science Park

In 1970 a Cambridge college committed its own land and endowment on a multi-decade horizon, seeding a cluster that now spans thousands of knowledge companies.

Lesson: a patient landowner with a long horizon incubates a cluster.
Cambridge cluster: ~5,000 firms · 61,000 people · £15.5B turnover
Visit ↗
Singapore

One-North

The state developer built the district and moved national research institutes in first, beside the National University, so the district had serious tenants from its first day.

Lesson: an anchor research tenant draws the rest.
200 hectares · ~S$15B program · A*STAR + NUS
Visit ↗

And across the United States

The American model began at Research Triangle Park: three universities, a governor, and business leaders placing a district in a neutral nonprofit so rival schools could cooperate and the work could move at private speed. The cases that follow refine the same idea, from a university acting like an owner to a mission nonprofit paired with a specialist developer.

North Carolina

Research Triangle Park

Duke, UNC, and NC State, with the governor and business leaders, placed the district in a neutral private nonprofit, chosen deliberately so rival universities could cooperate and the effort could move at private speed.

Lesson: a neutral nonprofit lets competitors collaborate and moves fast.
7,000 acres · ~400 companies · 55,000 jobs · $25.1B impact
Visit ↗
Cambridge, MA

Kendall Square · MIT

MIT acted as a deliberate developer of land it had long held, winning a city upzoning and building one of the densest innovation clusters in the world next to its own campus.

Lesson: give a university a real stake and it behaves like an owner.
Often called the densest innovation mile · 13 of the top 20 biopharma on site
Visit ↗
Philadelphia

uCity Square

A university-backed nonprofit joined a specialist developer and an institutional capital partner in a joint venture, splitting mission from execution cleanly.

Lesson: a mission nonprofit plus a specialist developer is a proven pairing, the role Now City plays here.
15,000+ workers · 200+ life-science companies · 1,000+ homes
Visit ↗
Reading Across The Cases

Which patterns each district actually ran

Read down a column to see how complete a district's playbook was. Read across a row to see how universal a pattern is. The scoring below is ours, and the notes underneath include a correction we had to make to it.

PatternCortex
St. Louis
Brainport
Eindhoven
Kista
Stockholm
Adlershof
Berlin
22@
Barcelona
Newlab
Navy Yard
The district
intent
Coalition formed before the real estate●●●○–●●
A neutral entity holds the mission●●●●○●●
One shared building came first○–●––●●
Researchers physically on site○●●●●○●
A public financing tool paired with the anchor●○○●●●●
Community seated in governance○––––●●
Homes inside the district○●●●●–●
● present    ○ partial    – absent. These are our readings of published accounts of each district rather than the districts' own self-assessments, and reasonable people would score some cells differently.
A correction we owe this page. An earlier version of this table claimed almost none of these districts had homes. That was wrong, and the real picture is more useful. Brookings, in the 2014 report that gave the term its meaning, defines an innovation district as offering mixed-use housing alongside the work. So housing is not our invention. It is the orthodoxy, unevenly applied.
What the record shows. A minority built housing in from the start: One-North had residential in its 2001 masterplan, Barcelona's 2000 rezoning legally required 4,000 subsidized homes, and Mission Rock in San Francisco is 40% affordable by design. More added it later under pressure: Adlershof now has around 3,900 homes, and Cortex broke ground on its first 174 apartments in 2026 after two decades. A famous few still have none, including the Brooklyn Navy Yard by industrial zoning. Two caveats worth carrying: Barcelona's 4,000 units were a requirement rather than a delivery, with roughly 1,581 built or under construction twenty-five years on, and the peer-reviewed critique of this field is that the housing which does get built skews expensive and pushes out the people already nearby. That is the failure shared equity is in our plan to avoid.
The Hub Model

Newlab is the model for one building

Newlab is the clearest model we have found for the workspace at the center of a district: a venture and maker community for hard technology in one rehabilitated industrial building, giving founders infrastructure to prototype, real projects to pilot and a path to capital. It is also one building inside a gated industrial campus, closed in the evening, with the nearest homes somewhere else. The hub is what we borrow. The neighborhood around it is what we add.

Inside Newlab in Building 128 at the Brooklyn Navy Yard
Inside Newlab: Building 128, an 1899 Navy machine shop rebuilt as a maker community
Interior of a raw high-bay bow-truss industrial building in West Salem
West Salem's raw, high-bay industrial stock: a similar building type, still standing
A shared maker hall inside a reused bow-truss warehouse with robotics tables, greenhouse test beds and families learning together
What a hub could be in a West Salem building: robotics tables, growing beds and studio pods under the trusses that are already there.

What Newlab is

Founded in 2016 by David Belt and Scott Cohen, modeled on the MIT Media Lab, inside Building 128, an 1899 Navy machine shop rebuilt as roughly 84,000 square feet of studios, labs, and a full fabrication shop, metal, wood, 3D printing, electronics, and CNC.

How it was built

A public landlord owned and rehabbed the shell; a private operator brought the vision and the curation. The roughly $82.8M Building 128 project drew $25M of New Markets Tax Credits alongside historic tax credits, federal, state, and city grants, and private capital. A coalition built it.

Why the hub model grew

Shared tools, a curated membership and real pilot projects reinforce each other. Newlab reports more than 300 member startups and over 1,000 members across its locations, and has opened a second site at Michigan Central in Detroit with Ford. The model has transferred once already.

The figures we cite for Newlab and the Brooklyn Navy Yard come from those organizations and the New Markets Tax Credit Coalition. The Building 128 capital stack ($25M of New Markets Tax Credits within a roughly $82.8M project) is documented; member counts are as the organizations report them.
How These Districts Are Built

The four partners

The same structure appears in most of these districts. Four partners come together, a university, a government, an industry and a community, and a neutral entity holds the mission so no single party owns it. The pattern is usually called the triple helix, with the community as a fourth strand.

Each partner brings what the others cannot: the university its research and talent, government its land and patient capital, industry its anchor demand and jobs, and the community its workforce and its stake in the result. The case studies below show it.

Innovation district stewardship model: a neutral district trust at the center holds the mission and convenes university, government, industry, and community
The Coalition

Who would build it

This is a starting point for conversations, not a roster. The precedents suggest which kinds of partner a district needs and roughly when. Which specific institutions fill each role is open, and in most of the cases we studied the answer changed once the work started.

Role

What that partner brings

Where we would look

Research

Applied research programs, graduate talent, and shared instrumentation that no single company would buy alone.

Oregon's research universities, particularly those holding federal Tech Hub designations, and robotics and precision-agriculture programs in and beyond the state.

Education and workforce

The pipeline that fills the jobs, from technician through engineer, plus small-business support for the companies that spin out.

Community colleges and in-town universities already running robotics, industrial electronics and machining programs in Salem, with apprenticeship partners in advanced manufacturing.

City and land

Land, entitlement, infrastructure and value-capture financing. In most of these precedents the public tool arrived alongside the anchor rather than after it.

The City of Salem and its Urban Renewal Agency, working through the Riverfront-Downtown urban renewal area.

State

Incentives, site readiness, and alignment with the federal programs the state already leads.

Business Oregon and the state's regional coordination function.

Regional convener

The standing table that holds employers, training and capital together between announcements.

The Mid-Willamette Valley's public-private economic-development organization, which already convenes this group.

Anchor

Founding tenancy and the credibility that makes the second commitment easier. The hardest seat to fill and the one that sets the timeline.

Four kinds are described below, drawn from what actually happened in the precedents.

Community

Legitimacy, workforce, and a seat in governance from the start rather than a consultation later.

West Salem neighborhoods, tribal partners, and the organizations already representing the valley's agricultural workforce.

The Hardest Seat

What an anchor actually is

In these districts one commitment usually came first and made the rest possible. The anchors were not all the same kind of organization, and the difference is worth understanding before deciding who to ask.

A health system

At Cortex, hospital and university anchors pooled roughly $29M and formed a nonprofit master developer. A health system has long-horizon capital, a permanent local presence, and a research mission. In Salem the regional care economy is the obvious place to look, and the health institute concept is one route to that conversation.

A research institute placed on site

Berlin moved university science faculties physically to Adlershof. Singapore moved national research institutes into One-North before the private tenants arrived. A relocated lab is the strongest possible signal, and the most expensive to arrange.

A dominant regional employer

Eindhoven organized around one company's supply chain and its people. This is the fastest route and the most fragile, because the district's fortunes track a single firm. Salem has candidates in advanced manufacturing and logistics; none has been approached about this.

A public revenue engine

Medellin funded Ruta N from a publicly owned utility's dividends and seated citizens as a full partner. The anchor need not be a tenant at all. It can be a durable source of money with a public mandate attached.

Named institutions above are where the conversation would start, based on what each already does. None of them has committed to anything described on this page, and we would expect the eventual list to look different.
The Approach · Built to Suit

Adaptive reuse first

Start with the buildings that are already standing. The district grows one building at a time, adapting West Salem's raw high-bay industrial stock to suit makers, ventures and labs, and adding purpose-built facilities as demand appears. Reuse is faster, lower-carbon and cheaper to finance, and a retrofit can draw historic and New Markets tax credits, as Newlab's Building 128 did. Newlab, Michigan Central and Greentown Labs all began this way. It also lets the district open early and grow on real occupancy.

Reuse first
existing industrial buildings rebuilt to suit shops, studios, labs, and demonstration
Build to suit
raw high-bay space adapted to what founders and anchors actually need
New as needed
purpose-built facilities added as demand appears
Walkable
a neighborhood where the technology can be tested in use

What gets built new

Purpose-built shared facilities follow demand: fabrication and instrumentation that no single company would buy alone, and the labs and high-bay space the applications on this page require. The order matters. Retrofit proves the occupancy that justifies the new construction.

A bow-truss warehouse converted into a live-work loft where a family cooks, builds and works on a small robot
A live-work loft under the old trusses
A cedar sauna club and cold plunge courtyard inserted into a reused industrial warehouse edge
A sauna club in a warehouse bay
A reused bow-truss warehouse opening onto a landscaped pedestrian lane with engineers, families, bikes and a new apartment block beyond
The frontage of a reused warehouse, opened onto a landscaped lane
Families and engineers using hand tools in a landscaped build yard beside a reused warehouse and a greenhouse frame
A build yard where the work is visible from the street
An evening live-work promenade beside reused bow-truss warehouses with warm interiors, families, bikes and planted paths
The live-work edge after dark
A rainy-day covered market arcade beside reused warehouses with produce stalls, bikes, hydroponics and stormwater planting
A covered arcade, so the market still works in the rain
↑